Macon has been the birthplace or hometown of such musicians as The Allman Brothers Band, Randy Crawford, Mark Heard, Lucille Hegamin, Otis Redding, Little Richard, Mike Mills and Bill Berry of R.E.M. The rapper Young Jeezy was discovered in Macon. September Hase, an alternative rock band, was discovered in Macon. Capricorn Records, run by Macon natives Phil Walden and briefly Alan Walden, made the city a hub for Southern rock music in the late 1960s and 1970s.
The Macon Symphony Orchestra performs at the Grand Opera House in downtown Macon, as well as a youth symphony, and the Middle Georgia Concert Band.